U wave

A 'U' wave as seen on Electrocardiogram (ECG)
An electrocardiogram of an 18-year-old male showing 'U' waves, most evident in lead V3.

The U wave is a wave on an electrocardiogram (ECG). It comes after the T wave of ventricular repolarization and may not always be observed as a result of its small size. 'U' waves are thought to represent repolarization of the Purkinje fibers.[1][2] However, the exact source of the U wave remains unclear. The most common theories for the origin are:

  • Delayed repolarization of Purkinje fibers
  • Prolonged re-polarisation of mid-myocardial M-cells
  • After-potentials resulting from mechanical forces in the ventricular wall
  • The repolarization of the papillary muscle.[3]
  1. ^ Pérez Riera AR, Ferreira C, Filho CF, et al. (2008). "The enigmatic sixth wave of the electrocardiogram: the U wave". Cardiol J. 15 (5): 408–21. PMID 18810715.
  2. ^ "ECG Learning Center - An introduction to clinical electrocardiography". ecg.utah.edu. Retrieved 2017-01-02.
  3. ^ F., Boron, Walter; L., Boulpaep, Emile (2012). Medical physiology : a cellular and molecular approach. ISBN 9781437717532. OCLC 756281854.{{cite book}}: CS1 maint: multiple names: authors list (link)

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